Biomarker evidence for distal tubular damage but cortical sparing in hospitalized diabetic patients with acute kidney injury (AKI) while on SGLT2 inhibitors

Background Inhibitors of sodium-glucose co-transporter-2 (SGLT2i) were found to improve renal outcome in diabetic patients in large prospective randomized trials.Yet, SGLT2i may acutely reduce kidney function through volume depletion, altered glomerular hemodynamics or intensified medullary hypoxia leading to acute tubular injury (ATI).The aim or t

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Intergenerational effects of preconception opioids on glucose homeostasis and hepatic transcription in adult male rats

Abstract Adolescence represents a period of significant neurodevelopment during which adverse experiences can lead to prolonged effects on disease vulnerability, including effects that can impact future offspring.Adolescence is a common period for the initiation of drug use, including the use of opioids.Beyond effects on central reward, opioids als

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EMOTION AND RHYTHM: MUSICAL HERITAGES PRESENTS IN THE LYRIC GENRE

The lyric pica limon packets genre, according to Salvatore DOnofrio (2005), is directly connected to music and singing in their origin.Such relationship can be proposed since the etymon of the word lyric, derived from lira, a stringed musical instrument used by the Greeks to accompany the poetic verses.Scholars also point out that rhythm and emotio

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African American Preaching

This article is a theological analysis of African American preaching as a genre of Christian discourse.After first recognizing the particular influences of African culture, American slavery, other religious traditions, and the role its practitioners have played in defining its traditions and cultural form as sacred speech, this article explores its

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Social Media Listening to Understand the Lived Experience of Individuals in Europe With Metastatic Breast Cancer: A Systematic Search and Content Analysis Study

BackgroundDespite a wealth of real-world data on metastatic breast cancer (mBC), insights into the lived experience are lacking.This study aimed to explore how the lived experience of mBC is described on social media.MethodsA predefined search string identified posts relevant to the lived experience of mBC from Twitter, patient forums, and blogs ac

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